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CLINICAL PIPELINE

We are a biopharmaceutical company that develops novel drugs. Our leading drug candidate is called REMOXY© (oxycodone) Extended-Release Capsules Cll. REMOXY is a strong painkiller with a unique formulation designed to reduce potential risks of unintended use. REMOXY and three other abuse-resistant painkillers are being developed pursuant to our strategic alliance with Pfizer, Inc.

We are also currently working on a variety of other preclinical programs.

PIPELINE STATUS

Drug Candidate Indication Phase Commercial Rights
Remoxy Moderate/severe chronic pain III Pfizer
PTI-202 Moderate/severe chronic pain I PTI
PTI-721 Moderate/severe chronic pain I PTI

Note: Our drug candidates are in development stages and have not yet been apporved by the U.S. Food and Drug Administration.